Thanks Karen! Should’ve known KSU would be behind those data.
I’m with you on the dangers of annona consumption (or should I say, effective lack thereof for most people)
Yeah, I'd love to see an update on KSU's work. This is the sort of problem that should be able to be effectively bred away, especially given what already appears to be significant genetic diversity in A. triloba.
Many if not most foods can kill you if you consume too much. Chocolate starts becoming toxic for your average adult at a dose of ~150 grams of raw cacao. About the same dose of nutmeg will cause you to start having hallucinations. Rhubarb's dangers when overconsumed, due to its oxalic acid, are well known - particularly with regards to kidney stones. Many oceanic fish, particularly ones high up on the food chain, can cause you to build up dangerous levels of mercury and other heavy metals / persistent organic compounds if overconsumed. Most commercial cinnamon contains coumarin, which is hepatotoxic and suggested to cause neurological damage in children when consumed during pregnancy; a teaspoon of cinnamon per day is above the recommended safe dose for smaller individuals. More than 5 brazil nuts per day puts one at risk of selenium overdose. Overconsumption of soy can cause anemia and endometrial hyperplasia. I mean, the list goes on and on. I think it's a bit more insidious with annonacin because there's such a delay between consumption and symptoms, and because it's a lot easier to picture how a person could pick up an annona-a-day habit versus, say, downing a couple tablespoons of nutmeg
Plus, if it is allowed to progress too far it can become a serious, irreversible condition. But the acetogen consumption levels just are too low for a "casual" annona consumer for it to be something to lose sleep over; the amount I consume is below that of the "control groups" in the studies! I'd question, given the studies I'd seen, whether lower-acetogenic fruits like biribá, sugar apple, atemoya, etc could even cause atypicla parkinsons
at all, given how much lower the levels are than in guanabana. I don't think a person could eat that much; I think it'd kill them through diabetes first with all those carbs
Anyway, "sola dosis facit venenum."