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UF 914 grapefruit cultivar is supposed to have little to no effect on statins.  I don't know if it has been released yet, though.


TFN
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Updated List
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Part list of drugs that interact with Furanocoumarins.:

ANTICANCER
Dasatinib (leukaemia)
Erlotinib (lung cancer and pancreatic cancer)
Everolimus (kidney cancer)
Lapatinib (breast cancer)
Nilotinib (leukaemia)
Pazopanib (kidney cancer)
Sunitinib (kidney/gastrointestinal cancer)
Vandetanib (thyroid cancer)
Venurafenib (skin cancer)
ANTI-INFECTIVE
Erythromycin (antibiotic)
Halofantrine (antimalaria)
Maraviroc (antiHIV)
Primaquine (antimalaria)
Quinine (antimalaria)
Rilpivirine (antiHIV)
ANTICHOLESTEROL
Atorvastatin
Lovastatin
Simvastatin
CARDIOVASCULAR
Amiodarone (heart rhythm disorders)
Apixaban (anticlotting)
L. Fidel et al.
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Dronedarone (heart rhythm disorders)
Eplerenone (heart failure)
Felodipine (high blood pressure/angina)
Nifedipine (high blood pressure/angina)
Quinidine (heart rhythm disorders)
Rivaroxaban (blood anticlotting)
Ticagrelor (blood anticlotting after heart attack)
CENTRAL NERVOUS SYSTEM
Oral alfentanil (painkiller)
Oral fentanyl (painkiller)
Oral ketamine (painkiller, sedative)
Lurasidone (schizophrenia/mental health problems)
Oxycodone (painkiller)
Pimozide (schizophrenia/other mental health problems)
Ziprasidone (schizophrenia, mania, bipolar disorder)
GASTROINTESTINAL
Domperidone (antinausea)
IMMUNOSUPPRESSANTS
Cyclosporine (post organ transplant, rheumatoid arthritis, psoriasis)
Sirolimus (post organ transplant)
Tacrolimus (post organ transplant)
URINARY TRACT
Solifenacin (frequent urination/incontinence)
Silodosin (enlarged prostate)
Tamsulosin (enlarged prostate)

Source: http://www.cmaj.ca/content/185/4/309/tab-figures-data

This is the reason why Israely breeders are developing cultivars with the taste similar to grapefruit, but with low level of Furanocoumarin.
New cultivars:
Aliza Orah c. reticulata x Chandler citrus maxima
Cookie Frua c. reticulata x “Siamese Sweet citrus maxima

source: https://file.scirp.org/pdf/FNS_2016022315190052.pdf
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Citrus Buy, Sell, & Trade / Re: Japan citrus seeds
« Last post by Luisport on December 11, 2018, 06:08:06 AM »
Hi, Luisport.
Hyuganatzu(New summer orange) season is Apr-Jun.
I will contact you if get the fruits.
Thank you very much!  ;D
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Tropical Fruit Discussion / Re: Mango Pests, Diseases, and Nutritional Problems
« Last post by Guanabanus on December 11, 2018, 05:42:58 AM »
Drenching the soil, or spraying the leaves with an Azadirachtin-containing product, such as Aza-Sol (OMRI approved), will prevent immature scale and other insect pests from molting--- so no successful reproduction.
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Tropical Fruit Discussion / Re: Please help me save this M4 mango tree
« Last post by Guanabanus on December 11, 2018, 05:36:42 AM »
With trees in the ground, a very thin application of compost, like less than an inch will usually be ok, when you are wanting to encourage a lot of growth, as the compost tends to have quite a bit of Nitrogen.

Adding a couple of inches of tree-surgeon mulch (fresh, shredded prunings), instead of finished compost, seems to work best, as it it more slow-release.
Natural-materials mulch of leaves and small branches also works great around trees in the ground.

About potting up, you can pot up into a container as big as you like, PROVIDED the soil mix is mostly of NON-ORGANIC materials (i.e., not decomposable, carbon-based materials):  sand, Perlite, charcoal, bio-char, rock dusts, a little clay maybe, and only 5-10% by weight of slow-rotting bark or wood.  Make sure the pot has plenty of holes on the lower side and bottom.  Otherwise, the concerns about turning into a toxic anaerobic water rot, or low-oxygen swampy muck are very real, when you pot up a small-containerized plant into a huge container.
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Citrus General Discussion / Re: C35-Meyer lemon incompatibility
« Last post by mehmetsaygin on December 11, 2018, 04:35:43 AM »
Thank you very much Millet.
Actually the symptoms I see on internet don't look very similar to our situation. Also we haven't notice much problems on fruits. But in any case it is very easy to try applying the correct fungisit and check the result. We will see.

Have a nice day :)
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Tropical Fruit Discussion / Re: Please help me save this M4 mango tree
« Last post by jmart777 on December 11, 2018, 03:21:55 AM »
JM, when you get trees from the nursery, it is best to step up the size of the pot slowly. From the pictures you posted, it looks like you have a small plant inside a big pot. When I up pot, i usually use a pot that is about 1-2 inches deeper and/or wider.

Got it.  I will up-pot more gradually from now on.


That looks like hardwood mulch on top of the soil.  If it is I would remove it as it's to rich for it. Pine mulch would be a better choice.


I believe it is small fir bark.


Also avoid compost in mango pots.

Thanks for chiming in Har.  I do avoid placing the compost inside the mix in the pot, but I thought it was okay to top dress with compost.  Should I avoid compost completely with potted mango trees?  How do you feel about compost with mango trees in the ground?

Thanks,

Jorge
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Temperate Fruit Discussion / Re: Best Persimmon tree to buy
« Last post by Radoslav on December 11, 2018, 03:07:01 AM »
I can recommend Hana Fuyu, heavy bearer, sweet, no need pollinator.





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Tropical Fruit Discussion / Re: Mammey Apple
« Last post by luketrollope on December 11, 2018, 02:38:21 AM »
Friend there is not a lot of information on Mammea americana out there. I can tell you my experience with the tree. Firstly not a lot of Mammea americana will fruit on their own but some trees do fruit very well on their own  so I am thinking there is male female and hermaphrodite / self pollinating. Better to plant 3 trees it seems. The flowers are very beautiful and fragrant. The seeds take a few months to germinate but then grow very quickly. I think the seeds could be classified as semi recalcitrant and would store for several months if kept slightly moist. The trees are very hardy and tolerant of  flood and drought. They are a great ornamental, shade and screen tree. They don't drop a lot of branches but the wood is brittle.

As for the fruit it can be hard to judge when they are ready to pick but they seem to fall to the ground when they are ready. Often they are hard even when they drop and need to be ripened off the tree. I don't think it is ever possible to pick a fruit and eat it straight from the tree it needs to soften off the tree. I am thinking this may be a reason it has a reputation for being slightly toxic in that the fruit needs to be fully ripe and soft.  Even when the fruit is “soft” it is still quite hard and it is best to cut it with a knife. It is as hard as a hardish rock melon and a similar colour. The flavour is good not so strong flavour and is similar to a apricot but with a more fruity flavour. I have never experienced any ill effects from the fruit. I have a dog and kids and never worry about the tree. The seeds if they are poisonous would be very hard to swallow as they are very large and impossible to eat unless you happen to have a pet pelican.

I would like to know if anyone has mastered how to judge when they are ripe. There must be a way maybe by scratching them and looking for a colour change like with sapodilla or something else. I have just picked them when i think they look ready but some don't ripen properly like that they will soften eventually  but not be good. The ones off he ground all so not all ripen properly and that may be because fruit bats knock them off early.  Anyway I recommend the tree and am just about to plant about 10 more myself here as they do well  in my area in marginal soil.

Keep it fruity!
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